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Watch Intently (2)pentobarbital will reduce the extent or outcome of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Potent CYP3A4 inducers may possibly lower suvorexant efficacy; if enhanced suvorexant dose required, don't exceed twenty mg/daypentobarbital will reduce the extent or effect of dapsone by i